Emerging research suggests a compelling link between the ketogenic diet and alterations in DNA methylation patterns. This remarkable dietary approach, characterized by high fat intake and restricted carbohydrate consumption, may profoundly influence gene expression by modifying the epigenome. While the precise mechanisms remain under investigation,
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In the human genome, 5mC is frequently found in CpG dinucleotides, with these web-sites staying hotspots for mutations which include in tumor suppressor genes. as an example, CpG island (CGI) mutations throughout the coding location of p53, a gene associated with genome stabilization and cell cycle/apoptotic responses, contribute to ~25% of its ina